Diffuse infiltration of dermis and subcutaneous tissue
Bland border of advancing spindled, fibroblast-like cells interdigitating with fat and adnexal tissues
Uniform plump fibroblasts in monotonous storiform pattern, in a pinwheel configuration around vessels
Low to moderate nuclear mitotic rate
Little collagen
± multinucleated giant cells
Has a t(17;22) translocation resulting in deregulated expression of platelet-derived growth factor B
o Collagen, type I, alpha 1-platelet-derived growth factor beta fusion gene (COL1A1-PDGFB) detectable by means of reverse transcriptase-polymerase chain reaction or FISH
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